WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0000577 organism homeostasis metabolism variant

Description  Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control.

5 RNAi

WormBase ID
WBRNAi00083131
WBRNAi00083135
WBRNAi00083134
WBRNAi00083136
WBRNAi00061108

0 RNAi Not Observed

19 Children

Identifier Name Description
WBPhenotype:0000030 growth variant Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) compared to control animals.
WBPhenotype:0000041 osmotic integrity variant Any variation in the process involved in the maintenance of an internal equilibrium of water within an organism, compared to control.
WBPhenotype:0000547 starved Animals exhibit morphological characteristics that are the outcome of nutrient deprivation. In C. elegans, starved worms have fewer refractile granules in intestinal cells, making them appear pale. Strongly starved mutants are small and thin, and tend to retain fewer eggs than control animals.
WBPhenotype:0001998 hypersensitive to laser ablation Animals respond more severely to laser ablation than control animals subjected to the same laser ablation conditions.
WBPhenotype:0000743 RNAi response variant Animals exhibit variations in their response to gene silencing triggered by double stranded RNA (RNAi), compared to control.
WBPhenotype:0000738 organism environmental stimulus response variant The response to a change in the environment is altered compared to control.
WBPhenotype:0001781 hypersensitivity to mutagen Animals are more susceptible than control animals to the effects of a nucleic acid damaging agent. This increased susceptibility is often measured by an increase in the rate of spontaneous mutations or an increased lethality.
WBPhenotype:0000228 spontaneous mutation rate increased Animals accumulate a greater number of genetic lesions than control animals in the absence of an externally controlled mutagen. In C. elegans, this is often measured by observing the number of reversion events of a known mutant gene function over a couple generations.
WBPhenotype:0002051 ascaroside biosynthesis variant The production or regulation of ascaroside molecule populations differs from that of control animals.
WBPhenotype:0002029 metal homeostasis variant Variations in the regulation of levels, transport, and metabolism of metal ions within an organism compared to control.
WBPhenotype:0000027 organism metabolism processing variant Variations in the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances compared to control.
WBPhenotype:0002182 reactive oxygen species homeostasis variant Animals exhibit variations in endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals.
WBPhenotype:0002073 cation homeostasis variant Animals exhibit variations in the regulation of levels, transport, and metabolism of cations within a cell or between a cell and its external environment, compared to control.
WBPhenotype:0001207 protein signaling variant Any variation in a series of protein mediated signals that help relay information within the cell, and thereby affecting changes in the functioning of the cell, compared to control.
WBPhenotype:0002003 hydrogen peroxide homeostasis variant Animals exhibit variations in steady-state levels of hydrogen peroxide (H2O2) compared to control.
WBPhenotype:0002063 maintenance of gene silencing variant Animals differ from controls in the expression of genes targeted for silencing (gene inactivation) in subsequent generations via transcriptional or post-transcriptional processes.
WBPhenotype:0002603 protein toxicity response abnormal Animals exhibit an abnormal response to toxic proteins, either via exposure in the environment or expressed within the organism, compared to controls.
WBPhenotype:0002639 microbiome composition abnormal Animals exhibit specific or general variations in the composition of the microbiome at a body site compared to controls.
WBPhenotype:0002663 intracellular lipid surveillance response abnormal Cells of the animal exhibit variations in the intracellular lipid surveillance response, responsible for responding to and addressing lipid depletion inside of cells, compared to control.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0000576 organism physiology phenotype Animals exhibit variations in any physical or chemical process required for the organism to carry out its normal function or be able to perceive and respond to stimuli.

3 Phenotype Allele

Public Name
mg280
e128
tm3688

2 Phenotype Allele Not Observed

Public Name
tm3199
tm2994

1 Synonyms

Name Type
organism homeostasis metabolism abnormal