WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Phenotype : WBPhenotype:0000730 apoptosis variant

Description  Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell.

179 RNAi

WormBase ID
WBRNAi00085406
WBRNAi00085670
WBRNAi00085509
WBRNAi00085380
WBRNAi00085320
WBRNAi00085323
WBRNAi00085579
WBRNAi00085660
WBRNAi00064154
WBRNAi00085450
WBRNAi00085676
WBRNAi00085500
WBRNAi00085487
WBRNAi00085760
WBRNAi00085547
WBRNAi00085321
WBRNAi00085324
WBRNAi00085353
WBRNAi00085361
WBRNAi00085363
WBRNAi00085362
WBRNAi00085368
WBRNAi00085387
WBRNAi00085390
WBRNAi00085399
WBRNAi00085401
WBRNAi00085403
WBRNAi00085404
WBRNAi00085413
WBRNAi00085433

13 RNAi Not Observed

WormBase ID
WBRNAi00097423
WBRNAi00088816
WBRNAi00065417
WBRNAi00064145
WBRNAi00065418
WBRNAi00065424
WBRNAi00097448
WBRNAi00065425
WBRNAi00097449
WBRNAi00065428
WBRNAi00097584
WBRNAi00097789
WBRNAi00097788

13 Children

Identifier Name Description
WBPhenotype:0000183 apoptosis increased Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.
WBPhenotype:0000885 engulfment variant Any variation in the removal of a cell corpse, by a neighboring cell or a phagocyte compared to control.
WBPhenotype:0010004 cell corpse degradation variant Variations in the process(es) that constitute cell corpse degradation within the engulfing cell compared to control.
WBPhenotype:0000182 apoptosis reduced Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals.
WBPhenotype:0002201 apoptotic DNA degradation defective Dying animals cells exhibit defects in the fragmentation of chromosomal DNA into oligonucleosomal-length fragments compared to control animals. This process can be monitored by the quantity and quality of TUNEL (TdT-mediated dUTP nick end labeling)-positive nuclei.
WBPhenotype:0001218 cell death sexually dimorphic variant Animals exhibit variations in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations.
WBPhenotype:0000590 cell corpse number variant Animals exhibit differences in the number of cell corpses compared to controls at the same developmental life stage.
WBPhenotype:0002610 ectopic apoptosis Apoptosis occurs in cells or cell types that do not undergo apoptosis in controls.
WBPhenotype:0000185 apoptosis protracted Animals exhibit a decreased pace of the programmed cell death pathway, compared to that observed for control cells.
WBPhenotype:0002180 apoptotic cell shedding variant Animals exhibit variations in the process by which cells having undergone programmed cell death are shed or extruded into the extracellular environment.
WBPhenotype:0002184 starvation induced apoptosis variant Any variation in the amount of cells undergoing apoptosis in organism as a result of deprivation of nourishment, compared to control. In C. elegans, starvation normally causes increased apoptosis.
WBPhenotype:0002203 corpse morphology variant Corpses resulting from programmed cell death appear different in size or shape from those of corpses in control animals.
WBPhenotype:0002152 mutagen induced apoptosis variant Programmed cell death of germ cells caused by exposure to physical or chemical DNA-damaging agents does not occur to the same extent as it does in control animals.

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Parents

Identifier Name Description
WBPhenotype:0001172 programmed cell death variant Developmentally regulated termination of a cell or cell group does not occur as in control animals.

7 Phenotype Allele

Public Name
q325
e1996
ok171
n2744
ju4
ok1097
ses2509

23 Phenotype Allele Not Observed

Public Name
tm321
tm766
tm705
tm759
tm799
tm847
ok393
mg144
ok525
tm1473
op309
ns294
tm2301
tm1844
tm1913
tm2530
tm1459
tm1118
tm1866
tm1228
tm1966
ttTi5439
n4256

2 Synonyms

Name Type
Ced  
apoptosis abnormal