WormMine: Phenotype WBPhenotype:0001345 cytoskeleton organization biogenesis variant

• Description: Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

3 RNAi

WormBase ID
WBRNAi00063495
WBRNAi00063496
WBRNAi00063497

1 RNAi Not Observed

WormBase ID
WBRNAi00083443

2 Children

Identifier	Name	Description
WBPhenotype:0001587	actin organization biogenesis phenotype	Animals exhibit variations in the formation and/or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas).
WBPhenotype:0001588	microtubule organization biogenesis variant	Animals exhibit variations in the form, structure, composition or arrangement of a robust macromolecular array, composed primarily of tubulin, which forms long extended cytoskeletal elements compared to control (Wormatlas).

1 Data Sets

• WormBaseAcedbConverter

2 Parents

Identifier	Name	Description
WBPhenotype:0000519	physiology phenotype	Animals exhibit variations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal functions and activities or be able to perceive and respond to stimuli compared to control animals.
WBPhenotype:0001344	organelle organization biogenesis variant	Intracellular membrane bound compartments vary in shape or size from that observed in control animals.

12 Phenotype Allele

Public Name
qa4900
s1710
tm710
e1753
e1802
e1873
e1874
e1885
cu8
ky275
shy19
syb2774

0 Phenotype Allele Not Observed

1 Synonyms

• Name: cytoskeleton organization biogenesis abnormal