WormMine: Gene WBGene00221462

• WormBase Gene ID: WBGene00221462
• Gene Name: Bm1201
• Sequence Name: Bm1201
• Organism: Brugia malayi
• Automated Description: Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Chromadorea ALT and Chromadorea ALT protein. Is an ortholog of O. volvulus OVOC11668.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm1201.1	Bm1201.1		[unknown]

Other

1 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm1201	Bm1201		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

6 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M42
	Transcripts that showed significantly increased expression in male B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M42_vs_M30
	Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to female B. malayi 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M30_vs_F30
	Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_F120_vs_F30
	Transcripts that showed significantly decreased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_F30_vs_L4
	Transcripts that showed significantly decreased expression after 5 days of 300nM ivermectin exposure.	Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method).	WBPaper00049974:ivermectin_300nM_5-day_downregulated

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term