|
|
Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. |
Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. |
WBPaper00045439:BM_Cluster_P1
|
|
|
Transcripts that showed significantly lower expression in L3 larva comparing to in adult. |
edgeR v3.28. FDR < 0.05, fold change > 2. |
WBPaper00061765:L3_vs_Adult_Downregulated
|
|
|
Proteins that are enriched in digestive tract of adult female Brugia malayi. |
Protein quantitation was determined by normalized spectral abundance.Proteins with NSAF enrichment values of 2 or greater were were considered enriched within that fraction. |
WBPaper00048706:digestive-tract_enriched
|
|
|
Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP. |
Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering. |
WBPaper00045439:BM_Cluster_P13
|
|
|
Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to female B. malayi 30 days after infecting gerbils. |
EdgeR(v3.16.5), FDR < 0.05. |
WBPaper00051007:downregulated_M30_vs_F30
|
|
|
Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. |
EdgeR(v3.16.5), FDR < 0.05. |
WBPaper00051007:upregulated_F120_vs_F30
|
|
|
Transcripts that showed significantly lower expression in L4 larva comparing to in microfilariae. |
edgeR v3.28. FDR < 0.05, fold change > 2. |
WBPaper00061765:L4_vs_Micro_Downregulated
|
|
|
Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils. |
EdgeR(v3.16.5), FDR < 0.05. |
WBPaper00051007:upregulated_F120_vs_F42
|
|
|
Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to L4 male B. malayi animals. |
EdgeR(v3.16.5), FDR < 0.05. |
WBPaper00051007:downregulated_M30_vs_L4
|
|
|
Transcripts that showed significantly lower expression in L4 larva comparing to in adult. |
edgeR v3.28. FDR < 0.05, fold change > 2. |
WBPaper00061765:L4_vs_Adult_Downregulated
|
