1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003026 | lin-41 | C12C8.3 | Caenorhabditis elegans |
| WormBase ID | WBStrain00008559 | CGC Received | 2016-09-14 |
| Genotype | lin-41(xe8)/+ I. | Laboratory | HW |
| Name | HW1320 | Outcrossed | x3 |
| Remark | Heterozygous stock. Maintain strain by picking Egl heterozygous animals. xe8/xe8 homozygotes burst at the vulva. Heterozygous animals have egglaying defects (Egl). xe8 is a partial deletion of the lin-41 3'UTR eliminating ~450 nt that includes the two let-7 complementary sites (LCS) [I:9,335,206 - 9,335,654]. xe8 is a gain-of-function allele: elimination of two functionally relevant let-7 binding sites relieves repression by let-7 causing overexpression of LIN-41 in L4 stage animals. Reference: Ecsedi M, et al. Dev Cell. 2015 Feb 9;32(3):335-44. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. | Species | Caenorhabditis elegans |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003026 | lin-41 | C12C8.3 | Caenorhabditis elegans |
