WormBase Gene ID
|
RGD:1598210 | Gene Name | RNF220 |
| Organism | Rattus norvegicus | Automated Description | Predicted to enable beta-catenin binding activity and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of canonical Wnt signaling pathway; protein autoubiquitination; and regulation of postsynaptic neurotransmitter receptor internalization. Predicted to act upstream of or within dorsal/ventral neural tube patterning; noradrenergic neuron development; and protein monoubiquitination. Predicted to be located in cytoplasm and nuclear lamina. Predicted to be part of protein-containing complex. Predicted to be active in glutamatergic synapse and postsynapse. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 23. Orthologous to human RNF220 (ring finger protein 220); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; amitrole. |
| Biotype | SO:0001217 | Genetic Position | :± |
