Is predicted to encode a protein with the following domains: E3 ubiquitin-protein ligase synoviolin/Hrd1; Ring finger domain; Zinc finger, RING-type; and Zinc finger, RING/FYVE/PHD-type. Is an ortholog of C. elegans sel-11. In C. elegans, sel-11 is involved in regulation of Notch signaling pathway and regulation of gene expression.