WormMine: Gene WBGene00259688

• WormBase Gene ID: WBGene00259688
• Gene Name: SRAE_1000307100
• Sequence Name: SRAE_1000307100
• Organism: Strongyloides ratti
• Automated Description: Is predicted to encode a protein with the following domains: Integrin beta subunit, VWA domain; Integrin domain superfamily; von Willebrand factor A-like domain superfamily; Integrin beta epidermal growth factor like domain 1; EGF-like domain; Integrin beta tail domain superfamily; Integrin plexin domain; Integrin beta N-terminal; Integrin beta subunit, tail; Integrin beta cytoplasmic domain; Integrin beta tail domain; Integrin beta subunit; Integrin beta subunit, cytoplasmic domain; Integrin beta, epidermal growth factor-like domain 1; Integrin beta chain VWA domain; and EGF-like domain, extracellular. Is an ortholog of C. elegans pat-3. In C. elegans, pat-3 is involved in several processes, including muscle cell cellular homeostasis; positive regulation of cellular component organization; and regulation of locomotion.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Strongyloides ratti
• Taxon Id: 34506

0 Synonyms

Genomics

1 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:SRAE_1000307100.1	SRAE_1000307100.1		[unknown]

Other

1 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:SRAE_1000307100	SRAE_1000307100		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

3 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
parasitic vs free-living.	Transcripts that showed significantly decreased expression at infective third-stage larva stage, comparing to free living female stage.	Differentially expressed genes in all pairwise comparisons (parasitic vs. free-living; parasitic vs. iL3; and iL3 vs. free-living) were determined for S.ratti and S.stercoralis using the R (version 3.1.2) package edgeR version 3.6.8. Genes with less than one count per million reads were excluded. Genes were considered to be differentially expressed if the false discovery rate (FDR) was <= 0.001 and the fold change was >= 2.	WBPaper00050919:down_infective-L3_vs_free-living_mRNA
parasitic vs free-living.	Transcripts that showed significantly decreased expression at parasitic female stage (collected from S. ratti-infected rats), comparing to free living female stage.	Differentially expressed genes in all pairwise comparisons (parasitic vs. free-living; parasitic vs. iL3; and iL3 vs. free-living) were determined for S.ratti and S.stercoralis using the R (version 3.1.2) package edgeR version 3.6.8. Genes with less than one count per million reads were excluded. Genes were considered to be differentially expressed if the false discovery rate (FDR) was <= 0.001 and the fold change was >= 2.	WBPaper00050919:down_parasitic_vs_free-living_mRNA
parasitic vs free-living.	Proteins that showed significantly decreased expression at parasitic female stage (collected from S. ratti-infected rats), comparing to free living female stage.	Significant differences were analyzed statistically by ANOVA. Q-values are adjusted P values and were calculated by Progenesis based on an optimized false discovery (FDR) approach. A protein was considered to be differentially expressed if q < 0.05.	WBPaper00050919:down_parasitic_vs_free-living_protein

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term