WormBase Gene ID
|
RGD:1306616 | Gene Name | Mcm5 |
| Organism | Rattus norvegicus | Automated Description | Predicted to enable single-stranded DNA binding activity. Predicted to contribute to 3'-5' DNA helicase activity and single-stranded DNA helicase activity. Predicted to be involved in DNA replication initiation; DNA unwinding involved in DNA replication; and double-strand break repair via break-induced replication. Predicted to be located in nucleoplasm. Predicted to be part of CMG complex and MCM complex. Predicted to be active in nucleus. Biomarker of alcohol use disorder. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 8. Orthologous to human MCM5 (minichromosome maintenance complex component 5); PARTICIPATES IN cell cycle pathway, mitotic; DNA replication pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine. |
| Biotype | SO:0001217 | Genetic Position | :± |
