WormBase Gene ID
|
RGD:1305947 | Gene Name | IFT57 |
| Organism | Rattus norvegicus | Automated Description | Predicted to be involved in intraciliary transport and non-motile cilium assembly. Predicted to act upstream of or within several processes, including epithelial tube morphogenesis; motile cilium assembly; and negative regulation of keratinocyte proliferation. Predicted to be located in several cellular components, including ciliary base; cytoskeleton; and photoreceptor connecting cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in Golgi apparatus; centrosome; and cilium. Human ortholog(s) of this gene implicated in orofaciodigital syndrome. Orthologous to human IFT57 (intraflagellar transport 57); PARTICIPATES IN Huntington's disease pathway; INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bisphenol A. |
| Biotype | SO:0001217 | Genetic Position | :± |
