WormBase Gene ID
|
RGD:1310201 | Gene Name | Alx4 |
| Organism | Rattus norvegicus | Automated Description | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in hair follicle development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including embryonic limb morphogenesis; embryonic skeletal system morphogenesis; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of transcription regulator complex. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in craniosynostosis; frontonasal dysplasia 2; gastrointestinal system cancer (multiple); lung cancer (multiple); and parietal foramina. Orthologous to human ALX4 (ALX homeobox 4); INTERACTS WITH alpha-Zearalanol; atrazine; bisphenol A. |
| Biotype | SO:0001217 | Genetic Position | :± |
