WormBase Gene ID
|
FB:FBgn0031773 | Gene Name | Fbw5 |
| Organism | Drosophila melanogaster | Automated Description | F-box and WD repeat domain containing 5 (Fbw5) encodes a protein that targets proteins for destruction via its role as a substrate receptor for the CRL4 E3 ubiquitin ligase. A key target of the product of Fbw5 is the subunit of the tuberous sclerosis complex encoded by gig, an important negative regulator of cellular growth via inhibition of the TOR kinase pathway. |
| Biotype | SO:0001217 | Genetic Position | :± |
