WormMine: Gene WBGene00224522

• WormBase Gene ID: WBGene00224522
• Gene Name: Bma-sip-1.4
• Sequence Name: Bm4261
• Organism: Brugia malayi
• Automated Description: Enriched in female based on proteomic studies. Is predicted to encode a protein with the following domains: Alpha crystallin/Hsp20 domain; Hsp20/alpha crystallin family; HSP20-like chaperone; and Alpha crystallin/Small heat shock protein, animal type. Is an ortholog of C. elegans sip-1. In C. elegans, sip-1 is involved in determination of adult lifespan; embryo development; and response to heat.
• Biotype: SO:0001217
• Genetic Position: :±

1 Organism

• Name: Brugia malayi
• Taxon Id: 6279

0 Synonyms

Genomics

2 Transcripts

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
Transcript:Bm4261b.1	Bm4261b.1		[unknown]
Transcript:Bm4261a.1	Bm4261a.1		[unknown]

Other

2 CDSs

WormMine ID	Sequence Name	Length (nt)	Chromosome Location
CDS:Bm4261a	Bm4261a		[unknown]
CDS:Bm4261b	Bm4261b		[unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

• WormBaseAcedbConverter

0 Downstream Intergenic Region

6 Expression Clusters

Regulated By Treatment	Description	Algorithm	Primary Identifier
	Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:downregulated_M120_vs_F120
	Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M120_vs_M42
	Transcripts that showed significantly increased expression in male B. malayi 42 days after infecting gerbils, comparing to female B. malayi 42 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M42_vs_F42
	Transcripts that showed significantly increased expression in male B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils.	EdgeR(v3.16.5), FDR < 0.05.	WBPaper00051007:upregulated_M42_vs_M30
	Time-course transcript abundance profiles. P116, k-means clusters of Brugia malayi during development in Aedes aegypti LVP between day 1 and 8 post infection; H114, k-means clusters of Ae. aegypti LVP infected with B. malayi between day 0 and 8 post infection; and HR14, host response profile comparing infected vs. uninfected A. aegypti LVP.	Non-flat profiles (p < 0.01 and maximum fold-difference among time points > 2) were grouped into common temporal patterns using k-means clustering.	WBPaper00045439:BM_Cluster_P6
	Proteins that were enriched in female animals.	Criteria used for protein identification included: two or more peptide matches, MASCOT score > 60, and P < 0.05.	WBPaper00041323:female-associated

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term