WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr4905 Remark  Picture: Fig 2.
Subcellular Localization  Endogenous MBK-2 and EGG-3 colocalize on the cortex of growing oocytes. Two MBK-2 fusions (GFP:MBK-2 and MBK-2:HIS) colocalize with endogenous EGG-3 on the cortex in metaphase I embryos and in discrete cytoplasmic puncta during the second meiotic division. In 2-cell and later embryos, EGG-3 was rarely detected, whereas GFP:MBK-2 and endogenous MBK-2 persisted in the cytoplasm of all blastomeres and on P granules until at least the 20-cell stage. Comparison of total EGG-3 levels to cytoplasmic GFP:MBK-2 levels confirmed that degradation of EGG-3 correlates with increased GFP:MBK-2 in the cytoplasm.

0 Anatomy Terms

2 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003150 mbk-2 F49E11.1 Caenorhabditis elegans
WBGene00009701 egg-3 F44F4.2 Caenorhabditis elegans

0 Life Stages