WormMine: ExpressionPattern Expr9661

• Pattern: We observed during the L1 stage mab-10 transcripts in the anterior and posterior bulbs of the pharynx as well as a small number of transcripts throughout the hypoderm. L2-stage animals showed increased expression of mab-10 mRNA in hyp7 and the rectal epithelium in addition to the nerve ring and the ventral nerve cord, where several cells contained one or two transcripts. During the early L3 stage, mab-10 was weakly expressed in hyp7 but showed high expression in the vulval and uterine precursor cells. mab-10 mRNA was also present within the distal tip cells and a pair of bilaterally symmetric cells that we believe to be the CAN neurons, based on their position and neuronal nuclear morphology. By the late L3 stage, mab-10 expression was almost absent from hyp7 but was high in the seam cells, distal tip cells and developing vulva. mab-10 transcript was also detected in the gonadal sheath cells. During the L4 stage, mab-10 transcripts dramatically increased in abundance throughout the pharynx, hypoderm and somatic gonad, including the distal tip cells.
• Primary Identifier: Expr9661

12 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
somatic cell that situates at the tip of a gonad arm.	distal tip cell	DTC	WBbt:0006865
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring.	ventral nerve cord	ventral cord	WBbt:0005829
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749
entire syncytium of hyp7	hyp7 syncytium	hyp7	WBbt:0005734
five pairs of thin gonadal sheath cells form a single layer covering the germ line component of each arm, each pair occupying a stereotyped position along the gonad proximal-distal axis.	gonadal sheath cell		WBbt:0005828
epithelium connecting intestine and anus.	rectal epithelium		WBbt:0005800
The components of the gonad that are separate from the germline proper. In hermaphrodite, these include five tissues which are all derived from the somatic primordium : the distal tip cells, the gonadal sheath, the spermatheca, the spermatheca-uterine valve (sp-ut) and the uterus.	somatic gonad	somatic germline	WBbt:0005785
cell that has the potential to form structural part of a vulva.	vulval precursor cell	VPC	WBbt:0007809
Constituent cell of a hermaphrodite vulva.	vulval cell	vulval epithelial cell	WBbt:0007831

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003107	mab-10	R166.1	Caenorhabditis elegans

4 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024