WormMine: ExpressionPattern Expr9608

• Pattern: The embryonic expression pattern of hlh-16 is largely bilaterally symmetric, with the notable exception of asymmetric expression in several distinct, otherwise bilaterally symmetric neuron pairs. Specifically, we detected the expression of hlh-16 reporters (hlh-16prom::mcherry and hlh-16trans::gfp) in two symmetric neuroblasts (ABplpapaaa and ABprpapaaa).These two neuroblasts generate through an asymmetric cell division one SMDD motoneuron and one AIY interneuron on each side of the animal. Following terminal division, the hlh-16 reporters are expressed in postmitotic SMDD(L/R) and AIY(L/R), and their expression decreases during larval development, becoming barely detectable in the adult. The hlh-16 reporters are expressed at a higher level in the left SMDD and AIY compared to the right SMDD and AIY. This L/R asymmetry is already visible in the SMDD/AIY mother cells. Asymmetric expression is also observed in their sister neuroblasts (the SIAD/SIBV mother cells) and, following terminal division, the SIAD and SIBV head motoneurons. Other bilateral neuron pairs display no asymmetric hlh-16 expression.
• Primary Identifier: Expr9608

10 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Amphid interneuron	AIYL	lineage name: ABplpapaaap	WBbt:0003963
Amphid interneuron	AIYR	lineage name: ABprpapaaap	WBbt:0003961
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDDL	lineage name: ABplpapaaaa	WBbt:0004972
Ring motor neuron/interneuron, has a posteriorly direct ed process that runs sublaterally	SMDDR	lineage name: ABprpapaaaa	WBbt:0004971
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIBVL	lineage name: ABplpapaapp	WBbt:0004978
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIBVR	lineage name: ABprpapaapp	WBbt:0004977
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIADL	lineage name: ABplpapaapa	WBbt:0004989
Receives a few synapses in the ring, has a posteriorly directed process that runs sublaterally	SIADR	lineage name: ABprpapaapa	WBbt:0004987
embryonic cell	ABplpapaaa		WBbt:0006679
embryonic cell	ABprpapaaa		WBbt:0006588

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001960	hlh-16	DY3.3	Caenorhabditis elegans

0 Life Stages