WormMine: ExpressionPattern Expr8882

• Primary Identifier: Expr8882
• Remark: Picture: Fig 3.
• Subcellular Localization: At the onset of morphogenesis, the expression of VANG-1 is detectable at the apical and basolateral domains of the intestinal epithelium. During more advanced morphogenesis, VANG-1 seems gradually to disappear from the apical membrane domain and becomes restricted to the basolateral domain. In later morphogenesis, VANG-1 predominantly localizes to the apex of intestinal cells and the staining pattern emerges in a structure, reminiscent to the CeAJ. Prior to hatching, most VANG-1 protein seems to localize at the CeAJ in the intestin. Double-labeling with anti-VANG-1 and anti-AJM-1 antibodies: Both proteins show a clear colocalization at the CeAJ in the intestine.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00015171	vang-1	B0410.2	Caenorhabditis elegans

0 Life Stages