WormMine: ExpressionPattern Expr3689

• Pattern: Animals produced expressing the wild-type DAT-1 translational fusion (BY312 vtIs6 [Pdat-1::GFP:DAT-1; rol-6]), displayed a readily detectable level of expression in all dopaminergic head neurons (CEP, ADE). This expression pattern is consistent with the DA neuron-specific expression of a dat-1 transcriptional fusion (BY200), described previously (see Paper cgc5147).
• Primary Identifier: Expr3689
• Remark: The GFP:DAT-1 fusion is functional in vivo since it fully restores 6-OHDA sensitivity to a (BY329 dat-1(ok157); vtIs6; vtIs7).
• Subcellular Localization: Expression of GFP:DAT-1 was observed along the plasma membrane of the CEP and ADE cell somas, out along dendrites, and in axons terminating in synapses localized to the nerve ring.

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Anterior deirid, sensory neuron, dopaminergic	ADEL	lineage name: ABplapaaaapa	WBbt:0004009
Anterior deirid, sensory neuron, dopaminergic	ADER	lineage name: ABprapaaaapa	WBbt:0004007
Cephalic neurons, contain dopamine	CEPDR	lineage name: ABarpapaappa	WBbt:0004937
Cephalic neurons, contain dopamine	CEPVL	lineage name: ABplpaappppa	WBbt:0004933
Cephalic neurons, contain dopamine	CEPVR	lineage name: ABprpaappppa	WBbt:0004931
Cephalic neurons, contain dopamine	CEPDL	lineage name: ABplaaaaappa	WBbt:0004938

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000934	dat-1	T23G5.5	Caenorhabditis elegans

0 Life Stages