1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004273 | rab-10 | T23H2.5 | Caenorhabditis elegans |
| Primary Identifier | Expr11666 | Subcellular Localization | Fluorescently labeled RAB-10 displayed partial overlap with markers for Golgi (Mannosidase II), endosomes (2xFYVE), and iDCVs (Syntaxin-6). No overlap was found with the ER marker cytochrome b5 (CB5) or the early Golgi/Coat protein complex I (COPI) vesicle marker (eCOP). In motoneuron axons mCherry-RAB-10 was largely diffuse and only partially colocalized with presynaptic markers, such as synaptic vesicle (SV) marker (YFP-RAB-3) and dense core vesicles (DCV) marker (NLP-21-YFP). DCVs are generally fewer in number at the active zone compared with SVs. Thus, it is likely that the partial localization of mCherry-RAB-10 at synaptic sites might suggest that RAB-10 is present on axonal DCVs. However, the strongest mCherry-RAB-10 signal was observed in motoneuron cell bodies where it partially colocalized with the DCV marker NLP-21-YFP, further suggesting that RAB-10 may be present on DCVs. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00004273 | rab-10 | T23H2.5 | Caenorhabditis elegans |
