WormMine

WS295

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr11812 Subcellular Localization  Between divisions, SYS-1 localizes weakly to the cortex and cytoplasm. Prior to metaphase, SYS-1 localizes to the nucleus and cytoplasm. During metaphase and anaphase, SYS-1 localizes to bright puncta that behave similarly to centrosomes. Centrosomal localization was confirmed by colocalizing mCherry::SYS-1 with GFP-tagged beta-tubulin, consistent with SYS-1 centrosomal localization observed in other tissues (Phillips et al., 2007; Huang et al., 2007). Asymmetric localization of SYS-1 is established during early telophase when SYS-1 levels are rapidly lowered in the anterior daughter while SYS-1 levels increase in the nuclear region of the posterior daughter. SYS-1 asymmetry is maintained after cytokinesis into late telophase when it localizes primarily to the nucleus of the posterior daughter. Within an hour after division, nuclear SYS-1 decreases and localization increases at the cortex and cytoplasm, but SYS-1 eventually becomes undetectable two hours after division.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00006379 sys-1 T23D8.9 Caenorhabditis elegans

0 Life Stages