1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00006379 | sys-1 | T23D8.9 | Caenorhabditis elegans |
Primary Identifier | Expr11812 | Subcellular Localization | Between divisions, SYS-1 localizes weakly to the cortex and cytoplasm. Prior to metaphase, SYS-1 localizes to the nucleus and cytoplasm. During metaphase and anaphase, SYS-1 localizes to bright puncta that behave similarly to centrosomes. Centrosomal localization was confirmed by colocalizing mCherry::SYS-1 with GFP-tagged beta-tubulin, consistent with SYS-1 centrosomal localization observed in other tissues (Phillips et al., 2007; Huang et al., 2007). Asymmetric localization of SYS-1 is established during early telophase when SYS-1 levels are rapidly lowered in the anterior daughter while SYS-1 levels increase in the nuclear region of the posterior daughter. SYS-1 asymmetry is maintained after cytokinesis into late telophase when it localizes primarily to the nucleus of the posterior daughter. Within an hour after division, nuclear SYS-1 decreases and localization increases at the cortex and cytoplasm, but SYS-1 eventually becomes undetectable two hours after division. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00006379 | sys-1 | T23D8.9 | Caenorhabditis elegans |