1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00017195 | glo-4 | F07C3.4 | Caenorhabditis elegans |
Primary Identifier | Expr4952 | Remark | Picture: Figure 2. |
Subcellular Localization | Coimmunostaining showed that in the ventral nerve cord, GLO-4::GFP was localized to discrete puncta adjacent to the SV protein SNT-1. In the cholinergic SAB motor neurons, GLO-4::GFP was localized at the anterior tip of the axon, while SNT-1 was localized at puncta throughout the length of the axon and excluded from the tip. This localization pattern is very similar to that of RPM-1. Coimmunostained GLO-4::GFP and endogenous RPM-1 and showed significant colocalization in the ventral cord, especially in regions that had high expression of RPM-1 Similarly, in the SAB neurons, GLO-4::GFP and RPM-1 colocalized at the anterior tip of the axon, where RPM-1 is most concentrated. To further confirm the colocalization of these two proteins at individual synapses in another type of neuron, authors expressed RPM-1::GFP and Cherry::GLO-4 in the type D GABAergic motor neurons using the unc-25 promoter. The D neurons form en passant synapses along the dorsal and ventral nerve cords. Cherry::GLO-4 and RPM-1::GFP colocalized to distinct puncta in the axons of these neurons. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00017195 | glo-4 | F07C3.4 | Caenorhabditis elegans |