WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Primary Identifier  Expr4952 Remark  Picture: Figure 2.
Subcellular Localization  Coimmunostaining showed that in the ventral nerve cord, GLO-4::GFP was localized to discrete puncta adjacent to the SV protein SNT-1. In the cholinergic SAB motor neurons, GLO-4::GFP was localized at the anterior tip of the axon, while SNT-1 was localized at puncta throughout the length of the axon and excluded from the tip. This localization pattern is very similar to that of RPM-1. Coimmunostained GLO-4::GFP and endogenous RPM-1 and showed significant colocalization in the ventral cord, especially in regions that had high expression of RPM-1 Similarly, in the SAB neurons, GLO-4::GFP and RPM-1 colocalized at the anterior tip of the axon, where RPM-1 is most concentrated. To further confirm the colocalization of these two proteins at individual synapses in another type of neuron, authors expressed RPM-1::GFP and Cherry::GLO-4 in the type D GABAergic motor neurons using the unc-25 promoter. The D neurons form en passant synapses along the dorsal and ventral nerve cords. Cherry::GLO-4 and RPM-1::GFP colocalized to distinct puncta in the axons of these neurons.

0 Anatomy Terms

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00017195 glo-4 F07C3.4 Caenorhabditis elegans

0 Life Stages