1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003210 | mel-28 | C38D4.3 | Caenorhabditis elegans |
| Primary Identifier | Expr4323 | Subcellular Localization | To investigate the dynamics of MEL-28 in living embryos, GFP-MEL-28 was compared with known NE proteins fused to G/YFP using confocal time-lapse microscopy. Like endogenous MEL-28, which was localized by immunostaining, GFP-MEL-28 was mostly concentrated at the nuclear periphery but was also detected in the nucleoplasm and associated with condensing chromosomes when cells entered mitosis. This pattern was indistinguishable from that of YFP-Nup107, which also localizes to kinetochores and is recruited very early during NE assembly. Consistent with previous reports, GFP-Nup155 associated with the NE approximately 60 s after anaphase onset when the integral NE protein LEM-2 began to concentrate around chromosomes. Thus, MEL-28 is present on chromatin before NE reassembly and earlier than most other NE components. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00003210 | mel-28 | C38D4.3 | Caenorhabditis elegans |
