WormMine: ExpressionPattern Expr11820

• Pattern: asic-1 is expressed in eight neurons comprising the C. elegans dopaminergic system (the four cephalic neurons; two anterior deirid neurons and two posterior deirid neurons; CEP, ADE, PDE, respectively). Expression is also detected in four additional neurons in the tail, two of which are the bilaterally symmetric PVQ interneurons.
• Primary Identifier: Expr11820
• Subcellular Localization: A full-length ASIC-1::GFP and an amino-terminal ASIC-1N::GFP chimaeras showed prominent punctuate distribution along the processes of dopaminergic neurons, in synapse-rich areas. A DsRED-synaptobrevin fusion colocalizes with both ASIC- 1::GFP and ASIC-1N::GFP in these puncta. Thus, ASIC-1 localizes at presynaptic termini of dopaminergic neurons.

12 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with its cell body situated in the tail, posterior to rectum.	tail neuron		WBbt:0006759
Neuron, dopaminergic of postderid sensillum	PDEL	lineage name: V5L.paaa	WBbt:0004383
Neuron, dopaminergic of postderid sensillum	PDER	lineage name: V5R.paaa	WBbt:0004382
Neuron that uses dopamine (DA) as a neurotransmitter.	dopaminergic neuron		WBbt:0006746
Interneuron, projects along ventral cord to ring	PVQL	lineage name: ABplapppaaa	WBbt:0004076
Interneuron, projects along ventral cord to ring	PVQR	lineage name: ABprapppaaa	WBbt:0004074
Anterior deirid, sensory neuron, dopaminergic	ADEL	lineage name: ABplapaaaapa	WBbt:0004009
Anterior deirid, sensory neuron, dopaminergic	ADER	lineage name: ABprapaaaapa	WBbt:0004007
Cephalic neurons, contain dopamine	CEPVL	lineage name: ABplpaappppa	WBbt:0004933
Cephalic neurons, contain dopamine	CEPVR	lineage name: ABprpaappppa	WBbt:0004931
Cephalic neurons, contain dopamine	CEPDL	lineage name: ABplaaaaappa	WBbt:0004938
Cephalic neurons, contain dopamine	CEPDR	lineage name: ABarpapaappa	WBbt:0004937

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00022815	asic-1	ZK770.1	Caenorhabditis elegans

0 Life Stages