1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00022880 | tbc-2 | ZK1248.10 | Caenorhabditis elegans |
| Primary Identifier | Expr9042 | Remark | Picture: Fig 4. |
| Subcellular Localization | mCherry::TBC-2 localizes to puncta and primarily colocalizes with RAB-7 and LMP-1 in the intestine, with some RAB-5 puncta, but not with RAB-11, suggesting that it localizes primarily with RAB-7 on late endosomes. The catalytically inactive TBC-2 R689K still shows a strong colocalization with RAB-7 and LMP-1 on the large late endosomes. Colocalization of mCherry::TBC-2 R689K with RAB-5 was observed, although to a lesser extent than RAB-7. No colocalization was detected with GFP::RAB-11 and mCherry::TBC-2 R689K. Thus, TBC-2 colocalizes predominantly with RAB-7 on late endosomes and to a lesser extent with RAB-5. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00022880 | tbc-2 | ZK1248.10 | Caenorhabditis elegans |
