WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  In strains that carry Pmbr-1::gfp, GFP expression was observed in restricted sets of interneurons in the head ganglia: AIM, RIC, RIH (or RIR), RIF (or RIG), and a pair of interneurons tentatively identified as AIN. Expression was also observed in three interneurons of the tail ganglia: PVP and an interneuron tentatively identified as DVA or DVC. In contrast, mbr-1::gfp was expressed in several more neurons compared to Pmbr-1::gfp, including sensory neurons. Expression of mbr-1::gfp was also detected in some intestinal cells at the late embryonic stages as well as in vulval cells and some somatic gonadal cells at the L4 stage. mbr-1::gfp expression becomes detectable first around the early comma stage, which corresponds to the time just after the birth of most neurons. Primary Identifier  Expr3681
Remark  The differences in the expression patterns of Pmbr-1::gfp and mbr-1::gfp might be due to the following reasons: first, additional regulatory elements might exist in introns and 3$(B!l(B-UTR regions, which are not included in the former construct; and second, as the product of Pmbr-1::gfp diffuses throughout the cytoplasm, it might be difficult to detect low levels of GFP expression. Subcellular Localization  The MBR-1::GFP fusion protein was localized to the nuclei, consistent with the idea that MBR-1 functions as a transcription factor.
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20 Anatomy Terms

Definition Name Synonym Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages. intestine gut WBbt:0005772
female genital. vulva   WBbt:0006748
Ring interneuron AIML lineage name: ABplpaapppa WBbt:0003983
Ring interneuron AIMR lineage name: ABprpaapppa WBbt:0003969
Ring interneuron RICL lineage name: ABplppaaaapp WBbt:0003941
Ring interneuron RICR lineage name: ABprppaaaapp WBbt:0003940
organ producing either sperm or ova. gonad   WBbt:0005175
neuron that senses external stimuli and transduce them to signals internal to the organism. sensory neuron   WBbt:0005759
Neuron class of one ring interneuron, cell body in dorsorectal ganglion, has a large vesicle-filled process in ring. DVA lineage name: ABprppppapp WBbt:0004823
Interneuron, cell body in lumbar ganglion, projects along ventral cord to nerve ring PVPL lineage name: ABplppppaaa WBbt:0004082
Interneuron, cell body in lumbar ganglion, projects along ventral cord to nerve ring PVPR lineage name: ABprppppaaa WBbt:0004078
Neuron class of one ring interneuron, cell body in dorsorectal ganglion. DVC lineage name: Caapaa WBbt:0004821
Ring interneuron RIGR lineage name: ABprppappaa WBbt:0003930
Ring interneuron RIGL lineage name: ABplppappaa WBbt:0003932
Ring interneuron RIFR lineage name: ABprppapaaap WBbt:0003934
Ring interneuron RIFL lineage name: ABplppapaaap WBbt:0003936
Neuron class of one ring interneuron. RIH lineage name: ABprpappaaa WBbt:0003928
Ring interneuron AINR lineage name: ABalaapaaar WBbt:0003965
Ring interneuron AINL lineage name: ABalaaaalal WBbt:0003967
Neuron class of one ring interneuron. RIR lineage name: ABprpapppaa WBbt:0005047

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00011315 mbr-1 T01C1.2 Caenorhabditis elegans

0 Life Stages