WormMine: ExpressionPattern Expr1682

• Pattern: AJM-1 localizes to the apical borders of all C. elegans epithelia. Expression occurs in the embryonic hypodermis, pharynx and intestine, as well as in post-embryonic epithelia, including the vulva, uterus, spermathecae, pharynx, intestine, hindgut, hypodermis and male tail. MH27 staining of embryos expressing HMP-1GFP reveals that AJM-1 occupies an apical domain that is basal to the HMRHMP(cadherincatenin) complex in all epithelial tissues examined. Transmission electron microscopy (TEM) analysis of embryonic hypodermal cell junctions revealed an apical junctional domain resembling adherens junctions of flies and vertebrates, whereas no morphologically distinct septate or tight junctions are observed. The apicobasal extent of this domain is ~100 nm. Immuno-TEM analysis of hypodermal cells of larvae with the MH27 antibody revealed that AJM-1 specifically localizes to the apical domain.
• Primary Identifier: Expr1682
• Subcellular Localization: AJM-1 localizes to the apical borders of all C. elegans epithelia.

1 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell of epithelium, the layer of cells that cover the external surface of an organism as well as forming an inner lining between the tissues and organs of that organism and the external environment. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells.	epithelial cell	epithelium	WBbt:0003672

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000100	ajm-1	C25A11.4	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	All C. elegans development stages, including embryo, larva and adult stage.		all stages Ce	WBls:0000002