WormMine: ExpressionPattern Expr11217

• Pattern: kpc-1 is expressed in numerous neuronal and epithelial cells during dauer. Processes adjacent to the body wall in dauers resemble those of IL2Q 4 dendrites. To determine whether kpc-1 is expressed in the IL2s, we coinjected the Pkpc-1::GFP reporter with a Pklp-6::tdTomato reporter that is expressed exclusively in the IL2s. During nondauer stages, kpc-1 is not expressed in the IL2 neurons (data not shown). In dauers, Pkpc-1::GFP and Pklp-6::tdTomato are coexpressed, indicating that kpc-1 is upregulated in the IL2s during dauer. Nondauer expression was consistently observed in the ventral nerve cord and pharynx with strong expression in the g2 pharyngeal gland cells and vpi pharyngeal intestinal valve cells.
• Primary Identifier: Expr11217

12 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A group of six equivalent cells forms a tightly constructed `valve` that links the posterior bulb of the pharynx to the anterior four cells of the intestine. These six cells comprise a small epithelial channel with a cuticular lining in continuity with the pharyngeal cuticle and link the lumen of the pharynx to the large lumen of the anterior intestine.	pharyngeal-intestinal valve	cardia	WBbt:0005767
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring.	ventral nerve cord	ventral cord	WBbt:0005829
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
Inner labial neuron	IL1DR	lineage name: ABalappppaaa	WBbt:0004737
cell of epithelium, the layer of cells that cover the external surface of an organism as well as forming an inner lining between the tissues and organs of that organism and the external environment. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells.	epithelial cell	epithelium	WBbt:0003672
Inner labial neuron	IL2VR	lineage name: ABarapppppp	WBbt:0004537
Inner labial neuron	IL2L	lineage name: ABalapaappp	WBbt:0004541
Inner labial neuron	IL2R	lineage name: ABalaappppp	WBbt:0004539
Inner labial neuron	IL2VL	lineage name: ABalppapppp	WBbt:0004538
Inner labial neuron	IL2DL	lineage name: ABalapappap	WBbt:0004545
Pharyngeal gland cell 2.	G2		WBbt:0003710

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002232	kpc-1	F11A6.1	Caenorhabditis elegans

3 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	A third stage larva specialized for dispersal and long term survival.		dauer larva Ce	WBls:0000032
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023