WormMine: ExpressionPattern Expr9952

• Pattern: CCDC- 55::GFP is broadly expressed in larvae and adults. The ccdc-55 message is transcribed as part of a multi-gene operon, CEOP3156, with the predicted promoter 5' of rnf-121. It is likely the expression pattern seen in the rnf-121::GFP animals is relevant for ccdc-55, this includes muscle, seam, hypodermis, vulva and somatic gonad with prominent expression in the DTC. In C. elegans, genes contained in operons can also be expressed independently (Blumenthal and Gleason, 2003), so the rnf- 121-based expression pattern may not completely recapitulate the endogenous expression of ccdc-55.
• Primary Identifier: Expr9952
• Subcellular Localization: Animals expressing a CCDC-55::GFP fusion protein in the DTC under the control of the lag-2 promoter were generated. In these animals, it was observed a nuclear and cytoplasmic distribution of CCDC-55::GFP in the DTC. However, the CCDC-55 localization was predominantly nuclear.

6 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
female genital.	vulva		WBbt:0006748
somatic cell that situates at the tip of a gonad arm.	distal tip cell	DTC	WBbt:0006865
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
Contractile cell that makes up muscle tissue.	muscle cell		WBbt:0003675
a group of hypodermal cells that lie along the apical midline of the hypodermis, at the extreme left and right sides between nose and tail	seam cell	lateral hypodermis	WBbt:0005753
The components of the gonad that are separate from the germline proper. In hermaphrodite, these include five tissues which are all derived from the somatic primordium : the distal tip cells, the gonadal sheath, the spermatheca, the spermatheca-uterine valve (sp-ut) and the uterus.	somatic gonad	somatic germline	WBbt:0005785

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00007627	ccdc-55	C16C10.6	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023