WormMine: ExpressionPattern Expr1650

• Pattern: LAD-1 visualized by immunofluorescence was expressed in all cells throughout development, starting at the onset of embryogenesis with its expression increasing dramatically during embryonic morphogenesis. LAD-1 was highly expressed in the nervous system. LAD-1 is localized to the plasma membrane of the cell bodies and axonal and dendritic processes and in nonneuronal tissues such as the pharynx, hypodermis, body wall muscles, and the germline. Localized LAD-1 was not detected in one-cell embryos, which lack sites of cellular contact.
• Primary Identifier: Expr1650
• Remark: No detailed description on postembryonic cellular localization.
• Subcellular Localization: LAD-1 is localized to the plasma membrane of the cell bodies and axonal and dendritic processes. LAD-1 was strikingly localized to the plasma membrane at sites of cellcell contact as early as just before the two-cell stage. Localized LAD-1 was not detected in one-cell embryos, which lack sites of cellular contact.

8 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring.	ventral nerve cord	ventral cord	WBbt:0005829
Longitudinal bands of muscle cells surrounding animal body, with one band running in each quadrant of the body, regulated contraction and relaxation of these muscles cause locomotion.	body wall musculature	body muscle	WBbt:0005813
Complement of nervous tissue (neurones, nerves, receptors and support cells) serving to detect, relay and coordinate information about an animal`s internal and external environments and to initiate and integrate its effector responses and activities.	nervous system		WBbt:0005735
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes.	nerve ring	circumpharyngeal nerve ring	WBbt:0006749

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00004732	sax-7	C18F3.2	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003