WormMine: ExpressionPattern Expr16023

• Pattern: We found that TSP-14A and TSP-14B exhibit distinct expression and localization patterns. First, only TSP-14A, but not TSP-14B, is detectable in the germline and sperm cells, as well as at the tip of the anterior sensory cilia, while TSP-14B is detectable in the pharynx. Both TSP-14A and TSP-14B are found in hypodermal cellsand the developing vulva. However, the two isoforms exhibit different subcellular localization patterns. In hypodermal cells, TSP-14A is primarily localized in intracellular vesicles, while TSP-14B is mainly localized on the cell surface. In the developing vulva, TSP-14A is localized on the apical side, while TSP-14B is localized on the basolateral membrane. Similar localization patterns hold true in the pharynx.
• Primary Identifier: Expr16023
• Remark: TSP-14B isoform expression.

3 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
the feeding organ, a neuro-muscular pump in the head of the animal, used to ingest food, bacteria suspended in liquid, filter them out, grind them up and transport posteriorly into the instestine.	pharynx	esophagus	WBbt:0003681
cell that has the potential to form structural part of a vulva.	vulval precursor cell	VPC	WBbt:0007809
primary cell type that forms the hypodermis.	hypodermal cell		WBbt:0007846

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006640	tsp-14	F39C12.3	Caenorhabditis elegans

0 Life Stages