WormMine: ExpressionPattern Expr1870

• Pattern: Expression of CFI-1 was identified in mid-late embryos (twofold and later) and throughout larval development and in the adult. CFI-1 was expressed in a small number of cells in the head and tail regions of the animals, with occasional faint staining in ventral cord neurons. In the head, only neurons and muscle cells expressed CFI-1. In the tail, only four neuronal cells expressed CFI-1. A cfi-1::GFP fusion gene was expressed in a pattern similar to that observed with anti-CFI-1 antisera. Using the cfi-1::GFP and anti-CFI-1 antisera a number of the cells expressing cfi-1 was identified based on their anatomical positions and neuronal morphologies. CFI-1 protein was expressed in IL2 and URA neurons, and in the AVD and PVC interneurons. Weaker expression was detected in the PVC sister neuron LUA. Most, if not all, head muscle cells expressed CFI-1, and m6 and m7 muscles in the pharynx expressed the protein as well. A small number of other cells also stained occasionally.
• Primary Identifier: Expr1870
• Subcellular Localization: CFI-1 protein is localized to nuclei of staining cells.

18 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
body wall muscle in the head, including first eight cells of each muscle quadrants which are innervated by nerve ring neurons.	head muscle	head body wall muscle	WBbt:0006761
Ventral cord interneuron, cell body in lumbar ganglion, synapses onto VB and DB motor neurons, formerly called delta.	PVCL	lineage name: ABplpppaapaa	WBbt:0004094
Ventral cord interneuron, cell body in lumbar ganglion, synapses onto VB and DB motor neurons, formerly called delta.	PVCR	lineage name: ABprpppaapaa	WBbt:0004092
seventh pharyngeal muscle cell layer	pm7	m7	WBbt:0003721
sixth pharyngeal muscle cell layer	pm6	m6	WBbt:0003724
Inner labial neuron	IL2VR	lineage name: ABarapppppp	WBbt:0004537
Inner labial neuron	IL2DR	lineage name: ABalappppap	WBbt:0004543
Inner labial neuron	IL2L	lineage name: ABalapaappp	WBbt:0004541
Inner labial neuron	IL2R	lineage name: ABalaappppp	WBbt:0004539
Inner labial neuron	IL2VL	lineage name: ABalppapppp	WBbt:0004538
Inner labial neuron	IL2DL	lineage name: ABalapappap	WBbt:0004545
Ventral cord interneuron, synapses onto VA, DA, AS motorneurons; formerly called delta.	AVDL	lineage name: ABalaaapalr	WBbt:0003866
Ventral cord interneuron, synapses onto VA, DA, AS motorneurons; formerly called delta.	AVDR	lineage name: ABalaaapprl	WBbt:0003865
Interneuron, short process in posterior ventral cord	LUAL	lineage name: ABplpppaapap	WBbt:0004493
Interneuron, short process in posterior ventral cord	LUAR	lineage name: ABprpppaapap	WBbt:0004491
Ring motor neuron	URAVR	lineage name: ABprpaaapaa	WBbt:0004934
Ring motor neuron	URADL	lineage name: ABplaaaaaaa	WBbt:0004940

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000476	cfi-1	T23D8.8	Caenorhabditis elegans

8 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The C. elegans life stage spanning 620-800min(hatch) after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. A stage after elongation is over. The last stage of embryogenesis. Also called pre-hatched embryo, late embryo or morphogenetic embryo.		fully-elongated embryo Ce	WBls:0000021
	The C. elegans life stage spanning 520-620min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and tripple fold. A stage between 2-fold embryo and fully-elongated embryo. Also called pretzel embryo or pretzel stage.		3-fold embryo Ce	WBls:0000020
	The C. elegans life stage spanning 460-520min after first cleavage at 20 Centigrade. Cell number remains at ~560 cells, with some new cells generated and some cells go through programmed cell death. The shape of embryo is elongated and double fold. A stage between 1.5-fold embryo and 3-fold embryo.		2-fold embryo Ce	WBls:0000019