1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00012532 | crp-1 | Y32F6B.3 | Caenorhabditis elegans |
| Primary Identifier | Expr8632 | Remark | Picture: Fig 5. Type: mammalian cell transfection. |
| Subcellular Localization | When expressed in NIH3T3 cells CRP-1 localized mainly in perinuclear punctuated structures. The subcellular localization of Myc-tagged CRP-1 was then assessed either by coexpression with GFP-tagged compartment specific markers or by staining CRP-1 expressing cells using compartment marker specific antibodies. CRP-1 did not significantly colocalize with BiP, ERGICp58, or anti-mannosidase II used, respectively, as markers for the endoplasmic reticulum, the ER-Golgi intermediate compartment or the Golgi apparatus. However, a subtle perinuclear colocalization of CRP-1 was observed with clathrin, as well as a very clear colocalization with transferrin receptors. These data indicate that CRP-1 most likely localizes to transferrin receptor enriched recycling endosomes and, to a lesser extent, to the trans-Golgi network (TGN) when expressed in NIH3T3 cells. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00012532 | crp-1 | Y32F6B.3 | Caenorhabditis elegans |
