| Pattern | GLS-1 is expressed in all germ cells, with the exception of spermatocytes. In the adult hermaphrodite, GLS-1 is present in the mitotic region, accumulates during early stages of meiotic prophase I and is slightly less abundant in maturing proximal oocytes. | Primary Identifier | Expr8620 |
| Remark | Picture: Fig 2. The ubiquitous GLS-1 expression overlaps the ubiquitous expression of GLD-3, yet GLS-1 and GLD-3 differ in their expression pattern during early and late meiotic prophase I. As a specificity control, authors stained germ lines extruded from gls-1 mutant animals. No immunoreactivity was observed with the monoclonal GLS-1 antibody, although GLD-3 and PGL-1 were readily detected. We conclude that GLS-1 expression and subcellular localization in the germ line is dynamic and largely overlaps with GLD-3. GLS-1 is present in oocytes, which suggests a possible maternal role for gls-1. | Subcellular Localization | In addition to a diffused cytoplasmic localization, a granular GLS-1 staining was observed in the most distal mitotic region and in germ cells entering meiotic diplotene in the proximal germ line. Almost all GLS-1 granules overlap with P granules, although GLS-1 intensities varied with respect to PGL-1 and GLH-2 intensities among P granules. This may reflect a selective enrichment of GLS-1 in P granules. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes. | germ line | germline | WBbt:0005784 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00007975 | gls-1 | C36B1.8 | Caenorhabditis elegans |
