WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  Immuno-histochemistry experiments reveal that DAF-18/PTEN and VAB-1/EphR are both expressed in the Z2/Z3 germline precursor cells, oocytes, as well as neuronal tissues. In the neuronal tissues, VAB-1/EphR is localized to the ventral nerve cord, nerve ring, and some head neurons. Primary Identifier  Expr8834
Remark  In the overexpressing line (quIs18) DAF-18/PTEN's neuronal expression is restricted to a subset of the head amphid neurons and is expressed weakly in the nerve cord. DAF-18::GFP was also detected in the amphids and ventral nerve cord. Picture: Fig 2. Subcellular Localization  VAB-1/EphR is expressed on the membrane of the proximal oocytes, whereas DAF-18/PTEN appears to show membrane and nuclear expression of multiple oocytes in both hermaphrodites and females.
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6 Anatomy Terms

Definition Name Synonym Primary Identifier
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring. ventral nerve cord ventral cord WBbt:0005829
neuron with its cell body situated in the head, excluding the pharynx. head neuron   WBbt:0006751
a female haploid germ cell. oocyte ovum WBbt:0006797
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes. nerve ring circumpharyngeal nerve ring WBbt:0006749
Germ line precursor cell Z3 lineage name: P4.a WBbt:0004575
Germ line precursor cell Z2 lineage name: P4.p WBbt:0004576

2 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000913 daf-18 T07A9.6 Caenorhabditis elegans
WBGene00006868 vab-1 M03A1.1 Caenorhabditis elegans

0 Life Stages