WormMine: ExpressionPattern Expr8234

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
A group of six equivalent cells forms a tightly constructed `valve` that links the posterior bulb of the pharynx to the anterior four cells of the intestine. These six cells comprise a small epithelial channel with a cuticular lining in continuity with the pharyngeal cuticle and link the lumen of the pharynx to the large lumen of the anterior intestine.	pharyngeal-intestinal valve	cardia	WBbt:0005767
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
Intestino-rectal valve	virL	lineage name: ABprpappppp	WBbt:0004511
Intestino-rectal valve	virR	lineage name: ABprpappppa	WBbt:0004510

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001251	elt-3	K02B9.4	Caenorhabditis elegans

Pattern	In the head, elt-3 GFP expression decreases with age in the hypodermal cells and the pharyngeal-intestinal valve cells, eventually showing little or no expression in old worms. In the trunk, elt-3 expression is mostly derived from the hypodermal cells and the intestinal cells, and expression in this region decreases quickly between day 3 and day 5 of adulthood. The elt-3 GFP reporter did not change expression in the intestinal-rectal valve cells located in the tail of the worm. In summary, these results show that age-related changes in elt-3 expression are complex, as different tissues show different kinetics of age regulation and some tissues show no age regulation at all.	Primary Identifier	Expr8234
Remark	Picture: Figures 1D and 1E.

WormMine