WormMine: ExpressionPattern Expr11462

• Pattern: When compared to the transgene of unc-4 promoter-driven regular GFP, the expression from uIs45 labeled far fewer cells at nearly every developmental stage. uIs45 expression began in DA neurons in 3-fold embryos and lasted until the middle of first larval (L1) stage. The reporter was expressed next in the VA neurons beginning with the most anterior cells during the L2 stage. This expression was lost soon afterward; by the late L2 stage the most posterior VA neurons had expressed and then lost the reporter. Although head neurons SAB, AVF, and I5 constantly expressed the reporter throughout the larval and adult stages, virtually no ventral cord neurons expressed it from the L3 to early L4 stage.The reporter was expressed in VC4 and VC5 (the vulval VC neurons) beginning at the same time as anchor cell invasion in early L4 animals. The expression stabilized in the mid-L4 when the hermaphrodite vulva formed and lasted throughout adulthood. The reporter was not observed in the other VC neurons at any time. In males, no ventral cord neuron expresses the reporter after L3 stage despite the expression in VA and DA neurons during earlier larval stages.
• Primary Identifier: Expr11462
• Remark: Temporal description

10 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Neuron class of nine ventral cord motor neuron, innervates dorsal muscle.	DA neuron		WBbt:0005278
Neuron class of twelve motoneurons, distributed along the ventral cord, which innervate ventral body muscles.	VA neuron		WBbt:0005339
Hermaphrodite specific ventral cord motor neuron innervates vulval muscles and ventral body muscles	VC4	lineage name: P6.aap	WBbt:0004617
Hermaphrodite specific ventral cord motor neuron innervates vulval muscles and ventral body muscles	VC5	lineage name: P7.aap	WBbt:0004613
Neuron class of one pharyngeal interneuron, posterior sensory.	I5 neuron	I5	WBbt:0004740
Interneuron, processes in ventral cord and ring, few synapses, right side	AVFR		WBbt:0005658
Interneuron, processes in ventral cord and ring, few synapses, left side	AVFL		WBbt:0005657
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1	SABD	lineage name: ABplppapaap	WBbt:0004999
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1	SABVL	lineage name: ABplppapaaaa	WBbt:0004998
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1	SABVR	lineage name: ABprppapaaaa	WBbt:0004997

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006744	unc-4	F26C11.2	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	A developmental life stage of the nematode Caenorhabditis elegans that occurs from egg hatching until adulthood.		larva Ce	WBls:0000023