WormMine: ExpressionPattern Expr9130

• Pattern: APL-1::GFP fluorescence is detected in the cell bodies and processes of nerve ring interneurons and the ventral cord. apl-1::gfp is also expressed in ocket cells and amphids present in the head. Strong expression is seen in junctional cells such as the pharyngeal intestinal valve, which tethers the pharynx to the intestine, and the uterine seam junction in adults, which provides the structural connection between the epidermis and the uterus. APL-1 can be weakly detected in many epidermal epithelia including hyp7, the hypodermal syncitium surrounding the worm, as well as vulval cells, rectal valve cells, pharyngeal arcade cells, and tail hypodermis. Expression is prominent in the excretory cell, a long H-shaped cell implicated in fluid balance. APL-1 was notably absent from body wall muscle and intestine.
• Primary Identifier: Expr9130
• Remark: Picture: Figure 1.
• Subcellular Localization: APL-1::GFP fluorescence is detected in the cell bodies and processes of nerve ring interneurons and the ventral cord.

16 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
neuron with cell body associated with the ventral nerve cord.	ventral cord neuron	ventral cord motoneuron	WBbt:0005300
female genital.	vulva		WBbt:0006748
A group of six equivalent cells forms a tightly constructed `valve` that links the posterior bulb of the pharynx to the anterior four cells of the intestine. These six cells comprise a small epithelial channel with a cuticular lining in continuity with the pharyngeal cuticle and link the lumen of the pharynx to the large lumen of the anterior intestine.	pharyngeal-intestinal valve	cardia	WBbt:0005767
H-shaped cell associated with the excretory system, largest cell in C. elegans.	excretory cell	excretory canal cell	WBbt:0005812
entire syncytium of hyp7	hyp7 syncytium	hyp7	WBbt:0005734
Interfacial (hypodermal) cells which connect the hypodermal epithelium of the lips to the pharyngeal epithelium, firmly binding the inner tissue (the pharynx) to the outer bodywall (the hypodermis).	arcade cell		WBbt:0005793
Tail ventral hypodermis	hyp10	lineage name: ABplppppppp	WBbt:0004378
Tail ventral hypodermis, 8th hypodermis cell	hyp8		WBbt:0004381
Tail ventral hypodermis, 9th hypodermis cell	hyp9		WBbt:0004380
Tail dorsal hypodermis	hyp11	lineage name: Cpappv	WBbt:0004377
neuron of the amphid sensillum	amphid neuron	amphid sensory neuron	WBbt:0005394
membranous cell attaches the uterus to the lateral epidermis (seam) and forms a thin laminar process dorsal to the vulva. formed by fusion of eight pi cell progeny and AC.	uterine seam cell	utse	WBbt:0006789
Intestino-rectal valve	virL	lineage name: ABprpappppp	WBbt:0004511
Intestino-rectal valve	virR	lineage name: ABprpappppa	WBbt:0004510
Preanal hypodermis	hyp12	lineage name: P12.pa	WBbt:0004376
	interneuron		WBbt:0005113

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000149	apl-1	C42D8.8	Caenorhabditis elegans

0 Life Stages