WormMine: ExpressionPattern Expr3085

• Pattern: After hatching, TRA-1 was still detected in SGPs, but its level and subcellular distribution were distinct in the two sexes. In hermaphrodite L1 SGPs, TRA-1 was largely nuclear, but in male L1 SGPs, TRA-1 was present at a lower level and was uniformly distributed between nucleus and cytoplasm. A similar sexually dimorphic difference was observed in the distribution of GFP::TRA-1 in L1 SGPs. The GFP::TRA-1 reporter partially rescued tra-1(0) mutants, indicating that it produces a functional protein. After the first SGP division, TRA-1 continues to be expressed in hermaphrodite gonads, but is no longer detectable in males. In wild-type XX embryos, TRA-1 was predominantly nuclear in SGPs from formation of the primordium, through embryogenesis, and into the first larval stage. Next, embryos from a fog-2 male/female strain was examined , which produces 50% XX and 50% XO progeny, to determine if TRA-1 is similarly expressed in male SGPs. In 2-fold embryos, most SGPs possessed nuclear TRA-1 (27/30). Therefore, TRA-1 is present in SGP nuclei of both XX hermaphrodite and XO male embryos.
• Primary Identifier: Expr3085
• Subcellular Localization: Expressed in nuclear and cytoplasm.

4 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Somatic gonad precursor cell	Z1	lineage name: MSpppaap	WBbt:0004577
Somatic gonad precursor cell	Z4	lineage name: MSappaap	WBbt:0004574
any of two cells that generate all somatic tissues of the gonad proper (i.e. ovary or testis ) and genital ducts (e.g. uterus, vas deferens).	somatic gonad precursor	SGP	WBbt:0007854
any of 20 large epithelial cells which form a tube and are mostly situated as bilaterally symmetric pairs around the tubular lumen. Each of these cell pairs forms an intestinal ring ( II-IX int rings). The most anterior intestinal ring (int ring I), however, is made of four cells. Intestinal cells contain large nuclei with large nucleoli and numerous autofluorescent granules in their cytoplasm.	intestinal cell		WBbt:0005792

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00006604	tra-1	Y47D3A.6	Caenorhabditis elegans

0 Life Stages