WormMine: ExpressionPattern Expr16175

• Pattern: The irk-1 promoter drove GFP expression in multiple neurons, including the hermaphrodite specific neuron (HSN), sensory phasmid neurons in the tail, and unidentified neurons in both the head and tail of male worms. Intestinal and gonadal cells were labeled as well. As would be predicted for all of the IRK proteins based upon homology with the mammalian Kir channels, clear plasma-membrane targeting of the GFP-tagged IRK-1 protein can be observed in the intestine. It is interesting that irk gene expression was notably absent in muscle and hypodermal cells.
• Primary Identifier: Expr16175

7 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
A chain of very large cuboidal cells forming a wide central lumen in which food arrives from the posterior pharynx, is digested, and from which waste products proceed to the rectum. Intestinal rings form in groups of two and four cells surrounding the common lumen; thus the epithelium is only one cell deep at any point, with neighboring cells firmly secured to their neighbors by apical adherens junctions. These cells have very large nuclei and many large vacuoles, yolk granules, and other inclusions; the latter increase in number and electron density as the animal ages.	intestine	gut	WBbt:0005772
neuron with its cell body situated in the head, excluding the pharynx.	head neuron		WBbt:0006751
neuron with its cell body situated in the tail, posterior to rectum.	tail neuron		WBbt:0006759
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNL	lineage name: ABplapppappa	WBbt:0004758
Herm. specific motor neurons (die in male embryo), innervate vulval muscles, serotonergic	HSNR	lineage name: ABprapppappa	WBbt:0004757
neuron of phasmid sensillum	phasmid neuron		WBbt:0006753
organ producing either sperm or ova.	gonad		WBbt:0005175

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00002149	irk-1	R03E9.4	Caenorhabditis elegans

0 Life Stages