WormMine: ExpressionPattern Expr1290

• Pattern: Immunocytochemistry using affinity-purified antibodies on fixed C. elegans embryos of varying ages revealed that AIR-1 is present on mitotic centrosomes. In the adult, AIR-1 staining was also found on the centrosomes of mitotic germ cells in the distal gonad.
• Primary Identifier: Expr1290
• Subcellular Localization: Diffuse cytoplasmic staining was found during interphase but, as cells entered mitosis, AIR-1 became localized to the centrosomes and remained associated with them throughout the mitotic phase of the cell cycle. Developmentally, AIR-1 was diffuse throughout oocytes and was not detected on the centrosomes of the sperm pronucleus. AIR-1 staining of centrosomes was initially detected in the first mitotic division following pronuclear fusion, and was present in all mitotic cells up to the limits of detection in the hundreds of cells comprising late-stage embryos.

3 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	posterior distal tip cell	gon herm dtc P	WBbt:0004506
Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	anterior distal tip cell	gon herm dtc A	WBbt:0004520
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00000098	air-1	K07C11.2	Caenorhabditis elegans

2 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003