WormMine: ExpressionPattern Expr1605

• Pattern: In adults, glh-1 and glh-2 RNAs are restricted to germ-line tissue. glh-1 RNA is present at all stages of germ-line development in the hermaphrodite gonad, from the distal region where germ cells divide mitotically through the proximal region where gametes mature. A similar pattern of strong glh-1 hybridization to all regions of the germ line is observed in males. The glh-2 message is at least 3-fold less abundant than glh-1 mRNA in the hermaphrodite germ line. The glh-2 signal is weakest in the distal mitotic region and most concentrated in the central meiotic region of the gonad. In addition, glh-2 RNA is barely detectable in males. Both glh-1 and glh-2 RNAs are detected in all cells of young embryos, with the level of hybridization much reduced after the 8- to 10-cell stage. Thus, while glh-1 and glh-2 RNA differ in their levels and their patterns of accumulation in hermaphrodite and male germ lines, both glh RNAs are found throughout the early embryo.
• Primary Identifier: Expr1605

2 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes.	germ line	germline	WBbt:0005784
organ producing either sperm or ova.	gonad		WBbt:0005175

2 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00001598	glh-1	T21G5.3	Caenorhabditis elegans
WBGene00001599	glh-2	C55B7.1	Caenorhabditis elegans

1 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	All C. elegans development stages, including embryo, larva and adult stage.		all stages Ce	WBls:0000002