| Pattern | Approximately two times more hoe-1 mRNA was observed in wild-type worms relative to glp-1(e2141ts) mutant worms. Quantitative real-time PCR analysis of the quantity of hoe-1 mRNA in adult glp-1(oz112) animals revealed a threefold to fourfold increase as compared to wild-type adults. Thus, the level of hoe-1 mRNA roughly correlates with the extent of proliferation of the germ line. | Primary Identifier | Expr2875 |
| Remark | Type: quantitative, real-time PCR analysis using RNA derived from adult wild-type worms, adult glp-1(e2141ts) mutant worms, which do not produce a germ line when grown at restrictive temperature, and adult glp-1(oz112) animals, which have a tumorous germline phenotype where germ cells never leave the mitotic cell cycle. If hoe-1 is expressed in the germ line, less hoe-1 message was expected to be seen in the glp-1(e2141ts) sample of RNA. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| cell line which early in development becomes differentiated from the remaining somatic cell line, and alone has the potential to undergo meiosis and form gametes. | germ line | germline | WBbt:0005784 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00001983 | elac-2 | E04A4.4 | Caenorhabditis elegans |
