WormMine: ExpressionPattern Expr3956

• Pattern: During hypodermal morphogenesis, GFP expression is seen in most cells within the embryo. Notably, it is cortically localized in all hypodermal cells. Interestingly, shortly after dorsal intercalation is completed, MIG-5 leaves the cortex and becomes more cytoplasmic in dorsal cells. Expressed throughout embryonic development. It is found in all cells of the early embryo. In most cells, the fusion protein is localized to the cell cortex, with only low levels remaining in the cytoplasm. In L1 larvae, the four-cell gonadal primordium is being established and polarized. MIG-5::GFP is expressed in both Z1 and Z4, which will eventually form the distal tip cells. During gonad migration, the DTCs display high levels of MIG-5::GFP. MIG-5::GFP is also present in the cells underlying the gonadal primordium, which become the VPCs and later it is present in the fully developed vulva. MIG-5::GFP is also present and cortically localized in both P11 and P12 and their progeny, P11.a, P11.p, P12.a and P12.p, and in SDQL and PVM, two of the neurons derived from the QL neuroblast.
• Primary Identifier: Expr3956
• Subcellular Localization: Expressed in the cell cortex, with low levels in the cytoplasm.

13 Anatomy Terms

Definition	Name	Synonym	Primary Identifier
Epidermal layer.	hypodermis	epidermis	WBbt:0005733
Posterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	posterior distal tip cell	gon herm dtc P	WBbt:0004506
Anterior distal tip cell, inhibit meiosis in neighbouring germ cells, lead gonad during morphogenesis, herm gonad	anterior distal tip cell	gon herm dtc A	WBbt:0004520
descendent cell of P11, posterior	P11.p		WBbt:0006899
descendent cell of P12, posterior	P12.p		WBbt:0006900
Postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1	P11	lineage name: ABplapappa	WBbt:0004410
Postembryonic blast cells for ventral cord motorneurons, ventral hypodermis, vulva, male preanal ganglion; ventral hypodermis in L1	P12	lineage name: ABprapappa	WBbt:0004409
Neuron class of one neuron, posterior ventral microtuble cell, touch receptor.	PVM	lineage name: QL.paa	WBbt:0004086
Somatic gonad precursor cell	Z1	lineage name: MSpppaap	WBbt:0004577
Somatic gonad precursor cell	Z4	lineage name: MSappaap	WBbt:0004574
descendent cell of P12, anterior	P12.a		WBbt:0006888
descendent cell of P11, anterior	P11.a		WBbt:0006887
Posterior lateral interneuron, process projects into ring	SDQL	lineage name: QL.pap	WBbt:0004993

1 Genes

WormBase Gene ID	Gene Name	Sequence Name	Organism
WBGene00003241	mig-5	T05C12.6	Caenorhabditis elegans

6 Life Stages

Remark	Definition	Other Name	Public Name	Primary Identifier
	The second stage larva. At 25 Centigrade, it ranges 25.5-32.5 hours after fertilization, 11.5-18.5 hours after hatch.		L2 larva Ce	WBls:0000027
	The fourth stage larva. At 25 Centigrade, it ranges 40-49.5 hours after fertilization, 26-35.5 hours after hatch.		L4 larva Ce	WBls:0000038
	The first stage larva. At 25 Centigrade, it ranges 14-25.5 hours after fertilization, 0-11.5 hours after hatch.		L1 larva Ce	WBls:0000024
	The stage that begins when a C.elegans individual is fully-developed and has reached maturity.		adult Ce	WBls:0000041
	The third stage larva. At 25 Centigrade, it ranges 32.5-40 hours after fertilization, 18.5-26 hours after hatch.		L3 larva Ce	WBls:0000035
	The whole period of embryogenesis in the nematode Caenorhabditis elegans, from the formation of an egg until hatching.		embryo Ce	WBls:0000003