1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00003834 | nxf-1 | C15H11.3 | Caenorhabditis elegans |
Primary Identifier | Expr9013 | Remark | Picture: Fig 5. |
Subcellular Localization | Anti-NXF-1 showed strong staining at the nuclear rim of somatic cells and germ cells. Co-staining experiments with anti-PGL-1 and anti-NXF-1 showed that nearly all the NXF-1 at the rim of germ nuclei is present at Pg-NPCs(nuclear pore complexes): surface views of nuclei showed a P granule in close association with the prominent patches of NXF-1 and cross-sections showed that NXF-1 was concentrated at the bases of P granules. In addition to staining at the nuclear rim, anti-NXF-1 stained foci at the center of most germ nuclei, a region occupied by the nucleolus. NXF-1 localization at the nuclear rim was very similar to NPP-9 localization. Indeed, the anti-NXF-1 and anti-NPP-9 antibodies showed strong competition for staining on formaldehyde-fixed nuclei, necessitating the use of a denaturing fixative. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00003834 | nxf-1 | C15H11.3 | Caenorhabditis elegans |