WormMine: AnatomyTerm WBbt:0005403

• Definition: neuron whose cell body is in the retrovesicular ganglion.
• Name: retrovesicular ganglion neuron
• Primary Identifier: WBbt:0005403
• Synonym: retrovesicular ganglion

20 Children

Definition	Name	Synonym	Primary Identifier
Ventral cord motor neuron, innervates ventral body muscles, also interneuron in ring	VB1	lineage name: P1.aaap	WBbt:0004643
Ventral cord motor neuron, innervates ventral body muscles	VB2	lineage name: W.aap	WBbt:0004641
Neuron class of one ventral cord interneuron, few synapses.	AVG	lineage name: ABprpapppap	WBbt:0003850
Ring interneuron	RIGR	lineage name: ABprppappaa	WBbt:0003930
Ring interneuron	RIGL	lineage name: ABplppappaa	WBbt:0003932
Ring interneuron	RIFR	lineage name: ABprppapaaap	WBbt:0003934
Ring interneuron	RIFL	lineage name: ABplppapaaap	WBbt:0003936
Ventral cord motor neuron, innervates dorsal muscles, no ventral counterpart	AS1	lineage name: P1.apa	WBbt:0003925
Interneuron, processes in ventral cord and ring, few synapses, right side	AVFR		WBbt:0005658
Interneuron, processes in ventral cord and ring, few synapses, left side	AVFL		WBbt:0005657
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1	SABD	lineage name: ABplppapaap	WBbt:0004999
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1	SABVL	lineage name: ABplppapaaaa	WBbt:0004998
Ring interneuron, anteriorly projecting process that runs sublaterally, synapses to anterior body muscles in L1	SABVR	lineage name: ABprppapaaaa	WBbt:0004997
Ventral cord motor neuron, innervates ventral body muscles, probably reciprocal inhibitor	VD2	lineage name: P1.app	WBbt:0004607
Ventral cord motor neuron, innervates ventral body muscles, probably reciprocal inhibitor	VD1	lineage name: W.pp	WBbt:0004609
Ventral cord motor neurons, innervate dorsal muscles	DA1	lineage name: ABprppapaap	WBbt:0004871
Ventral cord motor neuron, innervates ventral body muscles	VA1	lineage name: W.pa	WBbt:0004872
Ventral cord motor neurons, innervate dorsal muscles	DB2	lineage name: ABarappappa	WBbt:0004845
Ventral cord motor neurons, innervate dorsal muscles	DB1	lineage name: ABplpaaaapp	WBbt:0004846
Ventral cord motor neurons, reciprocal inhibitors, chnage synaptic pattern during postembryonic development	DD1	lineage name: ABplppappap	WBbt:0004839

0 Expression Clusters

17 Expression Patterns

• Primary Identifier: Expr946
• Remark: To compare the transcription pattern of the daf-1 promoter with the whole gene, the gfp cDNA was fused to the terminus of the daf-1 gene in a plasmid that included 2.6 kb of upstream sequence. Despite the fact that this transgene rescued the daf-1 Daf-c mutant phenotype, GFP fluorescence was not detected in rescued animals. Hence, these observations were limited to the daf-1 promoter fusion, which may not represent the expression pattern of the whole daf-1 gene if enhancer elements are present in introns or in 3' sequences.
• Pattern: GFP expression was observed in the head and the developing ventral nerve cord beginning in mid-stage embryos and continuing into adulthood. In the head, GFP was detected in more than twenty neurons in the anterior, lateral, ventral and retrovesicular ganglia. Fluorescent processes terminating at the tip of the head suggest that daf-1 is expressed in sensory neurons and in support cells in the amphids and inner labial sensilla. In the midbody, GFP was expressed in the ALM mechanosensory neurons and the PVT neuron, as well as one additional neuron pair. In the lumbar ganglia of the tail, five cells expressing GFP included phasmid neurons and PLN and PLM mechanosensory neurons. The daf-1 promoter also conferred gfp expression in nonneuronal cells, including a membranous sheath surrounding the distal end of the intestine and in the distal tip cell (DTC) of the gonad. In some lines, GFP was sometimes detected in the muscles of L4 and adult animals. In L1 larvae, daf-1 promoters is active in neurons in the head, as well as in the ventral cord and tail. The promoter continues to express GFP in dauer larvae from starved plates.

• Primary Identifier: Expr14157
• Pattern: ADL and ASI (both relatively dim), some pharyngeal neurons, other dim cells (could be neurons), inter/motorneuron from RVG, (PVQ), cells close to the tip of the nose (support cells?)

• Primary Identifier: Expr2267
• Remark: Since these gfp fusions lack the introns and the 3' untranslated region, they might be lacking potential regulatory sequences. In that case, the gfp expression patterns may not precisely represent those of the endogenous kin-8 gene. cam-1 is called kin-8 in this article.
• Pattern: Expressed in chemosensory neurons in amphid: ASH. Other sensory neurons: ADE, FLP. Touch receptor neurons: AVM, ALM, PVM, PLM. Amphid interneurons: AIY, AIZ. Other interneurons: RIC, RMG, RIS, DVA, AVA, AVE, PVC, AVK, PVQ. Interneurons?: ALN, BDU, SDQ. Ring motor/inter neurons: RMD, RMDV. Ring motor neurons: RMED, RMEV Five neurons out of the following six, RIV, AVH, AVB, AVJ, AVD, AIN. About seven neurons in retrovesicular ganglion. Pharyngeal muscles in procorpus and isthmus. M4 and several pharyngeal neurons. A part of intestine and a few body wall muscles near the head (weak). Distal tip cells (sometimes and weak). A few ventral motor neurons and seam cells (rarely and weak). The expression patterns did not appear to change through the larva to adult stages. Embryonic expression was also observed.

• Primary Identifier: Expr1709
• Remark: Transgenic lines were generated by coinjection of the nlp::gfp construct (5070 ng/ul) and lin-15 rescue construct (pJM24,100 ng/ul) into lin-15(n765ts) animals. At least two independent transgenic lines were analyzed for each nlp gene; 510 animals were scored per line. 1,1'-Dioctadecyl-3,3,3',3 -tetramethylindodicarbocyanine perchlorate (Molecular Probes) was used to stain amphid and phasmid neurons to facilitate identification.
• Pattern: Expressed in ASH, CAN, HSN, BDU, 5 head neurons, VNC, 3 RVG neurons, 1 tail neuron, intestine.

• Primary Identifier: Expr10755
• Pattern: Previous studies have shown that this particular nlp-14 promoter sequence drives expression of GFP reporters to a subset of nervous system cells common to both sexes: the sensory neurons ASI, ASK, ASE, PHA, two retrovesicular ganglion neurons, ventral nerve cord motor neurons and the interneuron PVT. We find that in the male Pnlp-14::GFP reporters are additionally expressed in male-specific PVY, PVX and two male-specific dorsal rectal ganglion cells.

• Primary Identifier: Expr1702
• Remark: Transgenic lines were generated by coinjection of the nlp::gfp construct (5070 ng/ul) and lin-15 rescue construct (pJM24,100 ng/ul) into lin-15(n765ts) animals. At least two independent transgenic lines were analyzed for each nlp gene; 510 animals were scored per line. 1,1'-Dioctadecyl-3,3,3',3 -tetramethylindodicarbocyanine perchlorate (Molecular Probes) was used to stain amphid and phasmid neurons to facilitate identification.
• Pattern: Expressed in ASK, ADL, HOB, 6 head neurons, 2 tail neurons, I2, g1D, pm6L, pm6R, 2 RVG, processes in pharynx, intestine.

• Primary Identifier: Expr1708
• Remark: Transgenic lines were generated by coinjection of the nlp::gfp construct (5070 ng/ul) and lin-15 rescue construct (pJM24,100 ng/ul) into lin-15(n765ts) animals. At least two independent transgenic lines were analyzed for each nlp gene; 510 animals were scored per line. 1,1'-Dioctadecyl-3,3,3',3 -tetramethylindodicarbocyanine perchlorate (Molecular Probes) was used to stain amphid and phasmid neurons to facilitate identification.
• Pattern: Expressed in ASI, ASK, ASE, PHA, VNC, 2 RVG neurons, intestine.

• Primary Identifier: Expr1701
• Remark: Transgenic lines were generated by coinjection of the nlp::gfp construct (5070 ng/ul) and lin-15 rescue construct (pJM24,100 ng/ul) into lin-15(n765ts) animals. At least two independent transgenic lines were analyzed for each nlp gene; 510 animals were scored per line. 1,1'-Dioctadecyl-3,3,3',3 -tetramethylindodicarbocyanine perchlorate (Molecular Probes) was used to stain amphid and phasmid neurons to facilitate identification.
• Pattern: Expressed in ADL, AFD, ASE, ASI, PHA, VNC, 4 head neurons, 2 RVG neurons.

• Primary Identifier: Expr13201
• Pattern: Four most posterior cells of the gut; Head neurons: ASE, AWA, AFD and 1 pair of neurons in the retrovesicular ganglion.

• Primary Identifier: Expr10991
• Pattern: elt-1 reporter gene expression was first seen around the 20-30 cell stage and was maintained during subsequent early embryogenesis in cells corresponding to hypodermal precursor cells. Just prior to morphogenesis, reporter gene expression could be seen in all the major hypodermal cell nuclei. During formation of the comma stage, embryo reporter gene expression declined in the dorsal and ventral hypodermis but remained high in the lateral seam cells. The seam-cell expression of the reporter gene continued throughout morphogenesis to the pretzel stage although at lower levels. In addition, at the threefold stage of development high levels of expression were seen in a group of cells adjacent to the pharynx in a position consistent with neuronal cells of the retrovesicular ganglion. During postembryonic development relatively low levels of expression were maintained in seam cells from the L1 to the adult stage as were high levels of ELT-1 in neuronal cells of the retrovesicular ganglion. ELT-1 expression was also clearly apparent in several different groups of neuronal cell bodies and axons; those of the ventral cord were the most prominent. Expression was also seen in several neurons in which the axon extended from the ventral cord and encircled the pharynx just in front of the posterior bulb.The reporter gene also showed postembryonic expression in sex-specific structures. In hermaphrodites, ELT-1 expression was seen in the vulval muscles (vm1 and vm2) and in males, in a subset of the lateral seam, the SET cells, that give rise to the sensory rays.

• Primary Identifier: Expr1182
• Pattern: Neurons in anterior, lateral, retrovesicular ganglia; seam cells.

• Primary Identifier: Expr1335
• Pattern: mig-13::GFP was first seen during embryogenesis in pharyngeal, hypodermal, and neuronal precursors located in the anterior body region. At hatching, mig-13::GFP was expressed in the pharyngeal-intestinal valve cells, as well as in the cell bodies and axons of a number of neurons in the retrovesicular ganglion and the ventral cord. Expression appeared to be restricted to cells in the anterior half of the body with the exception of DA9, which is located in the preanal ganglion. In later larval and adult stages, the same cells continued to express mig-13::GFP, although additional staining was seen in the postembryonically derived ventral cord neurons located in the anterior half of the animal. Significantly, no expression was seen in the migrating QR descendants.
• Subcellular Localization: MIG-13 appeared to be localized to the plasma membrane of all mig-13 expressing cells.

• Primary Identifier: Expr9908
• Pattern: Expressed in many neurons in nerve ring, RVG, and VNC.

• Primary Identifier: Expr13202
• Pattern: Anal depressor muscle; Subset of 12 striated head muscles (8 external, 4 internal); Neurons: 2 retrovesicular ganglion neurons, 2 neurons from the ventral ganglion, at least 16 neurons from the lateral ganglia, DVA or DVC.

• Primary Identifier: Expr1528
• Remark: kin-13 is called PKC1B in this article.
• Pattern: The transgene is expressed selectively and abundantly in nuclei of a group of neurons whose cell bodies lie immediately posterior to the nerve ring in the pharynx. These neurons are anterior, dorsal, ventral, lateral and retrovescular ganglia. PKC1B also expressed in tail ganglia. Expression not detected in the bulk (~75%) worm neurons or any other somatic cells.

• Primary Identifier: Expr1755
• Remark: Reference: personal communication from Oliver Hobert 2002-12-07.
• Pattern: Neuronal expression in: 4-6 cells in RVG; several classes of VNC-MNs; 4 labial sensory neurons Neuronal expression in: 4-6 cells in RVG; several classes of VNC-MNs; 4 labial sensory neurons.

• Primary Identifier: Expr2122
• Remark: Clone = pUL#L457 Other strains-- UL914, UL924 Strain = UL923
• Pattern: Expression is seen from the 2-fold embryonic stage until adulthood and is confined to neuronal cells of the nerve-ring, retrovesicular ganglion and the tail region. This gene has homology to Na+/K+/Cl- transporters.

0 Life Stages

2 Parents

Definition	Name	Synonym	Primary Identifier
Major cell type of nervous tissue, specialized for transmission of information in the form of patterns of impulses.	neuron	neurone	WBbt:0003679
Ganglion that lies at the anterior limit of the ventral nerve cord, near the ventral ganglion and nerve ring in the head posterior to the excretory pore. It is open and continuous with the region containing the motoneurons of the ventral cord. In the early L1 this ganglion holds 12 neuron cell bodies plus one neuroblast (Sulston and Horvitz, 1977; White et al., 1986). In the adult animal, the ganglion holds 20 neuron cell bodies.	retrovesicular ganglion		WBbt:0005656