| Primary Identifier | Expr10765 | Subcellular Localization | In early wild-type embryos, GPR-1/2 were localized both on the asters and the cell cortex. The cortical localization of GPR- 1/2 changed with the cell cycle. In one-cell embryos, GPR-1/2 were uniformly present at a low level on the cortex from early prophase to metaphase. The level of cortical localization of GPR-1/2 increased and became weakly enriched at the posterior pole of most embryos during anaphase. In some embryos with enriched posterior staining, GPR-1/2 also appeared to be slightly enriched at the anterior pole of the embryo, compared with lateral regions. GPR-1/2 asymmetry became more pronounced during cytokinesis and interphase of the two-cell stage. In the P1 blastomere during interphase, GPR-1/2 were highly enriched around the posterior pole of the cell, and were present at low levels uniformly around the cortex of AB. As the cell cycle progressed, GPR-1/2 asymmetry in P1 disappeared; GPR-1/2 were uniformly localized around the cortex through out prophase, metaphase and early anaphase. During late anaphase and telophase, GPR-1/2 were once again enriched at the posterior part of the P1 cell. These results indicate that GPR- 1/2 is asymmetrically localized in the P lineage. |
| Definition | Name | Synonym | Primary Identifier |
|---|---|---|---|
| A cell that is the P embryonic blast cell or is a lineal descendant of P. | P lineage cell | WBbt:0008590 |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00001688 | gpr-1 | F22B7.13 | Caenorhabditis elegans |
| WBGene00001689 | gpr-2 | C38C10.4 | Caenorhabditis elegans |
