1 Genes
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00000289 | cam-1 | C01G6.8 | Caenorhabditis elegans |
| Primary Identifier | Expr3509 | Subcellular Localization | CAM-1::YFP fluorescence could be detected in cholinergic motor neuron cell bodies and processes, typically outlining cell bodies in a manner consistent with localization to the cell membrane. In order to determine if CAM-1 expression in neuronal processes was associated with synapses, a transgenic strain was generated expressing both CAM-1::YFP and the synaptic vesicle marker SNB-1 fused to CFP. By using the acr-2 promoter to drive expression of SNB-1::CFP in cholinergic VA and VB motor neurons, CAM-1::YFP expression in cholinergic motor neurons was, in general, more diffuse than that of SNB-1::CFP. However, for regions in which punctate expression of CAM-1::YFP was detected, these puncta partially colocalized with SNB-1::CFP puncta. Interestingly, SNB-1::CFP puncta were identified that did not appear to be accompanied by an obvious area of increased CAM-1::YFP expression, suggesting that CAM-1 may be localized to a subset of cholinergic synapses. Occasionally, smaller CAM-1::YFP puncta that did not appear to be associated with obvious SNB-1::CFP puncta were also observed. |
| WormBase Gene ID | Gene Name | Sequence Name | Organism |
|---|---|---|---|
| WBGene00000289 | cam-1 | C01G6.8 | Caenorhabditis elegans |
