WormMine

WS294

Intermine data mining platform for C. elegans and related nematodes

Expression Pattern :

Pattern  The mau-2 mRNA levels were investigated in the germline by comparing wild-type young adults with adults carrying mutations that affect the germline. The mau-2 transcript level is extremely reduced in glp-4(bn2ts) mutants, which fail to develop a germline at 25C, indicating that most of the mau-2 mRNA in young adults is in the germline. Furthermore, the level of the mau-2 transcript is very high in fem-2(b245ts) mutants that make only oocytes at 25C, indicating that the oocytes are enriched with mau-2 transcript. However, the mau-2 transcript is very low in fem-3(q20ts) adults that make sperm only at 25C, indicating that the mau-2 transcript is not enriched in sperm. Taken together, these results indicate that oocytes accumulate high levels of mau-2 mRNA, presumably as a store to be used by the embryo. Primary Identifier  Expr3159
Remark  Consistent with these observations, in situ hybridization data reported in the Nematode Expression Pattern Database for clone yk462a, which corresponds to mau-2, show an intense signal in the germline of adults, particularly in the pachytene region. In addition, a strong level of mau-2 mRNA is detected at different embryonic stages, including as early as the two-cell stage.

1 Anatomy Terms

Definition Name Synonym Primary Identifier
a female haploid germ cell. oocyte ovum WBbt:0006797

1 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003136 mau-2 C09H6.3 Caenorhabditis elegans

0 Life Stages