1 Genes
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00003060 | lpd-3 | Y47G6A.23 | Caenorhabditis elegans |
Primary Identifier | Expr16380 | Subcellular Localization | We also used CRISPR/Cas9 to generate knock-in of seven copies of GFP11 at the C-terminus of endogenous LPD-3 and reconstitution with GFP1-10 revealed that endogenous LPD-3::GFP localized to ER and co-localized with mScarletlabeled EYST-2 and MAPPER, specific markers for ER-PM junctions40-42, but not with a Golgi marker. Thus, LPD-3 primarily localizes to the ER, particularly at the ER-PM membrane contact sites that are known to mediate lipid trafficking and integrate phospholipid regulation. |
WormBase Gene ID | Gene Name | Sequence Name | Organism |
---|---|---|---|
WBGene00003060 | lpd-3 | Y47G6A.23 | Caenorhabditis elegans |